This is just a mini poster of Samus befriending characters similar to her (in appearance) from other games. The girl on Samus's right (the left from your view) is Nova from Starcraft.
This may be the title page of a section of link67125's sprite comic: [link]
*I substituted Master Chief's assault rifle with a shotgun, because Rayg's spritesheet didn't have one.
Master Chief Sprite: Rayg